EPA issues test guidelines for: Testing pesticides and toxic substances, and; Developing test data for submission to the Agency for review under the: Toxic Substances Control Act (TSCA); Federal Insecticide, Fungicide and Rodenticide Act (FIFRA); and; Section 408 of the Federal Food, Drug and Cosmetic Act (FFDCA). Initial guidelines were issued in 1996 under the Office of Pollution Prevention and Toxics (OPPT) . Harmonized guidelines are issued in under the renamed Office of Chemical Safety and Pollution Prevention (OCSPP).
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